Responsibilities
Fusheng joined iPlant Collaborative in August 2011 as an iPlant Genotype to Phenotype (iPG2P) engagement team analyst (ETA). The ETA serves as a liason between scientific working groups, the iPlant software development team and iPlant leadership. This involves active discussion with the scientists, research into appropriate bioinformatics tools and supporting technologies, and the judicious application of technical judgment to convert working group conversation into practical design requirements. The primary responsibilities of the iPG2P Engagement Team Analyst include:
- Translation of working group discussions into formal software requirements
- Attending working group meetings and leading technical discussions
- Working with scientific collaborators to identify needs, articulate priorities, and develop workflows and narratives
- Tool research and evaluation, prototype software development and testing
- Managing and reporting on project requirements, progress, and deliverables
- Performing related duties as assigned by the iPG2P Scientific Lead and Project Manager
- Being proactive in identifying opportunities and potential problems
- Coordinating development across projects, facilitating integration and cross-communication
Research Expertise
- Genetics from genetic mapping to positional cloning
- Genomics from genetic and physical mapping to genome sequencing, assembling, and annotation, especially for barley, potato, and maize
- Genome structure, evolution, dynamics, and comparative genomics
- Plant disease resistance
Professional Experience
- G2P Scientific Analyst, iPlant Collaborative, University of Arizona, 2011-present
- Assistant Research Scientist, University of Arizona, 2003-2011
- Postdoc and Associate Specialist, University of California, Berkeley, 2001-2003
- Research Assistant, Iowa State University, 1995-2001
- Research Associate, Biotechnology Research Institute, CAAS, China
- Research Assistant, The Graduate School of CAAS, China
Selected Publications
- Schnable, P. S. #, Ware, D. #, Fulton R.S. ##, Stein, J. C. ##, Wei, F. ##, Pasternak, S., Liang, C., Zhang, J. ....(155 others)..., Wing, R.A. and Wilson, R.K. (2009). The B73 Maize Genome: Complexity, Diversity, and Dynamics. Science 326: 1112-115. (# Both authors contributed equally to this work. ## These authors contributed equally to data production and analysis).
- Wei, F., Zhang, J., Zhou, S., He, R., Schaeffer, M., ...(13 others)… Wilson, R.K. and Wing, R.A. (2009). The Physical and Genetic Framework of the Maize B73 Genome. PLoS Genetics 5(11):e1000715.
- Wei, F., Stein, J.S., Liang, C., Zhang, J., Fulton, R.S. ...(49 others)…, Wilson, R.K. and Wing, R. A. (2009). Detailed Analysis of a Contiguous 22-Mb Region of the Maize Genome. PLoS Genetics 5(11): e1000728.
- Zhou, S., Wei, F., Nguyen, J., Bechner, M., Potamousis, K., Goldstein, S., Pape, L., Mehan, M.R., Churas, C., Pasternak, S., Forrest, D.K., Wise, R., Ware, D., Wing, R.A., Waterman, M.S., Livny, M., Schwartz, D.C (2009). A single molecule scaffold for the maize genome. PLoS Genetics 5(11):e1000711.
Wei, F. and Wing R. A. (2008) The fruitful outcome of the papaya genome. Genome Biology 9:227.
- Wei, F., Coe,, E., Nelson, W., Bharti, A.K., Fred Engler, Goicoechea, J.L., Kim, H., Lee, S., Butler, E., Fuks, G., Schroeder, S., Fang, Z., McMullen,, M., Davis, G., Bowers, J., Paterson, A., Polacco, M., Gardiner, J., Cone, K., Messing, J., Soderlund, C., and Wing R.A. (2007). Physical and Genetic Structure of the Maize Genome Reflects Its Complex Evolutionary History. PLoS Genet 3: e123
- Bruggmann, R., A.K. Bharti, H. Gundlach, J. Lai, S. Young, A.C. Pontaroli, F. Wei, G. Haberer, G. Fuks, C. Du, C. Raymond, M.C. Estep, R. Liu, J.L.Bennetzen, A.P. Chan, P.D. Rabinowicz, J. Quackenbush, W.B. Barbazuk, R.A.Wing, B. Birren, C. Nusbaum, S. Rounsley, K.F. Mayer, and J. Messing. (2006). Uneven chromosomecontraction and expansion in the maize genome. Genome Res 16: 1241-1251
- Kuang, H.,* Wei, F.,* Marano, M.R.,* Wirtz, U.,* Wang, X.,* Liu, J., Shum, W.P., Zaborsky, J., Tallon, L. J., Rensink, W., Lobst, S., Zhang, P., Tornqvist, C., Tek, A., Bamberg, J., Helgeson, J., Fry, W., You, F., Luo, M., Jiang, J., Buell, R.C., & Baker, B (2005) The R1 resistance gene cluster contains three groups of independently evolving, type I R1 homologues and shows substantial structural variation among haplotypes of Solanum demissum. The Plant Journal 44:37-51. (* co-first authors).
- Nelson, W.M., Bharti, A.K., Butler E., Wei, F., Fuks, G., Kim H., Wing, R.A., Messing, J., and Soderlund, C. (2005) Whole-Genome Validation of High-Information-Content Fingerprinting. Plant Physiology 139: 27-38.
- Rice Chromosome 3 Sequencing Consortium. (2005) Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species. Genome Research 15:1284-1291. (As one of 72 authors)
- Messing, J., Bharti, A.K., Karlowski, W.M., Gundlach, H., Kim, H., Yu, Y., Wei, F., Fuks, G., Soderlund, C., Mayer, K.F.X., and Wing, R.A. (2004) Sequence composition and genome organization of maize. Proceedings of the National Academy of Sciences of the United States of America 101:14349-14354;
- Bharti, A.K., Wei, F., Butler, E., Yu, Y., Goicoechea, J.L., Kim., H., Fuks, G., Nelson., W., Hatfield, J., Gundlach, H., Karlowski, W.M., Raymond, C., Towey, S., Jaffe, D., Nusbaum, C., Birren, B., Mayer, K., Soderlund, C., Wing, R.A., and Messing, J. (2004) High-resolution physical mapping of the maize genome and sequencing a part thereof. Maize Genetic Cooperation Newsletter 78:47-49.
- Halterman, D., Wei, F., and Wise, R.P. (2003). Powdery mildew induced Mla mRNAs are alternatively spliced and contain mutiple upstream open reading frames. Plant Physiology 131:558-567.
- Wei, F., Wing, R.A. and Wise, R.P. (2002) Genome dynamics and evolution of the Mla (powdery mildew) resistance locus in barley. Plant Cell 14:1903-1917.
- Halterman, D., Zhou, F., Wei, F., Wise, R.P. and Schulze-Lefert, P. (2001). The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria graminis f. sp. hordei in barley and wheat. Plant Journal 25:335-348.
- Zhou,F., Kurth, J., Wei, F., Elliott, C., Valè, G., Yahiaoui, N., Keller, B., Somerville, S., Wise, R.P. and Schulze-Lefert, P. (2001). Cell-autonomous expression of barley Mla1 confers race-specific resistance to the powdery mildew fungus via a Rar1 independent signaling pathway. Plant Cell 13:337-350.
- Wise, RP, Wei, F. and Wing, R. (2000). Sequence analysis of the 270-kb Mla-spanning region reveals coupled defense gene families. Proceedings of the 8th International Barley Genetics Symposium. Vol. II, pp. 208-210. Adelaide, Australia.
- Wei, F, Gobelman-Werner, K. Morroll, S.M., Kurth, J., Mao, L., Wing, R., Leister, D., Schulze-Lefert, P., and Wise, R.P. (1999). The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppressed recombination within a 240-kb DNA interval on chromosome 5S (1HS) of barley. Genetics 153:1929-1948.
Synergistic Activities
- Instructor for Molecular Breeding Workshop, CAAS, China, 1992-1994
- Invited instructor for Cytogenetic and FPC Workshop, University of Wisconsin, 2007-2008
- Invited speaker at Plant and Animal Genome Meeting (2007)
- Invited speaker at Maize Genetics Conference (2007-2010)
- Invited reviewers for Genetics, MGG, TAG, and PMB (2000-present)
- Maintain the maize integrated genetic and physical map, and improve the maize pseudomolecules (2003-present)
- American Society of Plant Biologist (2008-present)
Education
- Ph.D, Iowa State University, 2001
- M.Sc. The Graduate School of CAAS, 1992
- B.A, Beijing (China) Agricultural University, 1989
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